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Abstract #0128

Blood Oxygenation of Human Fetal Brain in the Second and Third Trimester

Pavan Kumar Jella 1 , Uday Krishnamurthy 1,2 , Jaladhar Neelavalli 1,2 , Swati Mody 1 , Lami Yeo 3,4 , E. Hernandez-Andrade 3,4 , E. Ehterami 1 , M.D. Cabrera 1 , S.J. Korzeniewski 3 , E.M. Haacke 1,2 , Sonia Hassan 3 , and Roberto Romero 3

1 Department of Radiology, Wayne State University, Detroit, MI, United States, 2 Biomedical Engineering, Wayne State University, Detroit, MI, United States, 3 NICHD, NIH, DHHS, Perinatology Research Branch, Detroit, MI, United States, 4 Obstetrics and Gynecology, Wayne State University, Detroit, MI, United States

A major issue in studying fetal hypoxic ischemic injury (HII); utero in humans and its identification is limited and often the diagnosis is postponed till the post neonatal period when the injury becomes evident in neuroimaging. Hence, non-invasive imaging methods for assessing hypoxic-ischemic brain injury in-utero are of high clinical interest. Magnetic resonance (MR) susceptibility weighted imaging (SWI), was used to measure fetal blood oxygenation that helps in assessing difference in fetal oxygen utilization between second and third trimester.

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