Abstract #0143
R2* of water and fat in hepatic iron overload: implications for R2*-corrected fat quantification
Debra E. Horng 1,2 , Diego Hernando 1 , and Scott B. Reeder 1,2
1
Radiology, University of Wisconsin-Madison,
Madison, WI, United States,
2
Medical
Physics, University of Wisconsin-Madison, Madison, WI,
United States
Accurate fat quantification using chemical shift-encoded
techniques requires correction for R2* (=1/T2*) decay.
Correction for a common R2* for both fat and water
(single-R2*) has been shown to be accurate for FF
quantification in patients without iron overload. In
this work, the accuracy of single-R2* correction is
assessed in patients with iron overload. Fat-fraction
and R2* were measured in 42 subjects at 1.5T and 3.0T,
with both imaging and spectroscopy. The R2* of fat and
water are very similar even in the presence of iron
overload, showing that fat quantification with
single-R2* correction is accurate even for patients with
iron overload.
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