Abstract #0154
            Longitudinal texture changes to UTE-T2* following ACL reconstruction
                      Ashley Williams                     1                    , Yongxian Qian                     2                    , 						and Constance R Chu                     1          
            
            1
           
           Department of Orthopedic Surgery, Stanford 
						University, Stanford, CA, United States,
           
            2
           
           Radiology, 
						University of Pittsburgh, Pittsburgh, PA, United States
          
            
          This study tests the hypothesis that evaluation of the 
						spatial distribution of cartilage UTE-T2* values, 
						assessed via grey-level co-occurrence matrix texture 
						statistics, will better detect sub-surface damage and 
						disease progression to cartilage in ACL-injured subjects 
						than mean UTE-T2* alone. Both cross-sectional 
						comparisons with uninjured controls and longitudinal 
						evaluations of ACL-injured subjects over 2 years after 
						ligament reconstruction indicate that texture analyses 
						provide evidence of progressive cartilage degeneration 
						following ACL-injury that is not reflected in mean 
						UTE-T2* value. Texture evaluations in this work 
						augmented the ability of UTE-T2* mapping to 
						quantitatively monitor cartilage status in knees at risk 
						of developing OA.
         
 
            
				
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