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Abstract #0154

Longitudinal texture changes to UTE-T2* following ACL reconstruction

Ashley Williams 1 , Yongxian Qian 2 , and Constance R Chu 1

1 Department of Orthopedic Surgery, Stanford University, Stanford, CA, United States, 2 Radiology, University of Pittsburgh, Pittsburgh, PA, United States

This study tests the hypothesis that evaluation of the spatial distribution of cartilage UTE-T2* values, assessed via grey-level co-occurrence matrix texture statistics, will better detect sub-surface damage and disease progression to cartilage in ACL-injured subjects than mean UTE-T2* alone. Both cross-sectional comparisons with uninjured controls and longitudinal evaluations of ACL-injured subjects over 2 years after ligament reconstruction indicate that texture analyses provide evidence of progressive cartilage degeneration following ACL-injury that is not reflected in mean UTE-T2* value. Texture evaluations in this work augmented the ability of UTE-T2* mapping to quantitatively monitor cartilage status in knees at risk of developing OA.

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