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Abstract #0217

Interleaved Variable Density Sampling for Combined Dynamic Contrast Enhanced MRI and MRA of the Liver

Mahdi Salmani Rahimi 1 , Frank R Korosec 2,3 , Kang Wang 4 , James H Holmes 4 , Utaroh Motosugi 2 , Peter Bannas 2,5 , and Scott B Reeder 1,2

1 Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States, 2 Radiology, University of Wisconsin-Madison, Madison, WI, United States, 3 Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, 4 Global MR Applications and Workflow, GE Heatlhcare, Madison, WI, United States, 5 Radiology, University Hospital Hamburg-Eppendorf, Hamburg, Germany

High spatial and temporal resolution contrast enhanced MRI is the cornerstone of detection and characterization of focal liver lesions. An interleaved variable density undersampling pattern with dual-echo bipolar readouts and data-driven parallel imaging was modified to acquire volumetric images of the liver every four seconds. Parallel imaging calibration lines were only acquired once during the breath-hold. Images acquired in ten patients with focal nodular hyperplasia showed significant improvement in overall quality compared to clinical DCE images. MR angiograms were also obtained from the arterial phase of the time-resolved series, and were found to be comparable to the dedicated conventional MRA.

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