SNR and CNR Comparison of Single-Echo Dixon and Subtraction Contrast-Enhanced MR Angiography
Eric G. Stinson 1 , Joshua D. Trzasko 1 , Paul T. Weavers 1 , and Stephen J. Riederer 1
Mayo Clinic, Rochester, Minnesota, United
Single-echo Dixon-based methods can provide the benefits
(improved SNR, subtraction error reduction) of
Dixon-based contrast-enhanced MR angiography (CE-MRA)
without extending scan time. A theoretical SNR and CNR
analysis of single-echo Dixon compared to subtraction
CE-MRA was performed and compared to phantom and in vivo
results. Single-echo Dixon CE-MRA provides a contrast
concentration-dependent SNR and CNR boost of at least
over subtraction CE-MRA. At high contrast concentrations
(>3-4mmol) Gadolinium-induced susceptibility artifacts
can reduce the SNR and CNR of pre-calibrated Dixon CE-MRA.
This technique may allow time-resolved CE-MRA with
higher SNR and CNR and improved resistance to motion
than subtraction-based methods.
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