Abstract #0262
Imaging Temperature Changes in Cortical Bone Using Ultrashort Echo-Time MRI
Misung Han 1 , Serena J Scott 2,3 , Eugene Ozhinsky 1 , Vasant Salgaonkar 2 , Peder EZ Larson 1 , Chris J Diederich 2 , Viola Rieke 1 , and Roland Krug 1
1
Radiology and Biomedical Imaging, University
of California, San Francisco, San Francisco, CA, United
States,
2
Radiation
Oncology, University of California, San Francisco, San
Francisco, CA, United States,
3
Joint
Graduate Group in Bioengineering, University of
California San Francisco/Berkeley, San Francisco, CA,
United States
High-intensity focused ultrasound is a new, noninvasive
technique to ablate bone tumors and palliate pain. MR
thermometry is frequently employed to ensure proper heat
deposition to the targeted tumor and to prevent unwanted
damage to healthy tissues. However, conventional MR
thermometry based on the proton resonance frequency
(PRF) shift of water is not suitable for monitoring
temperature in cortical bone due to its short T2*
relaxation time. In this work, we demonstrate the
ability of 3D UTE imaging to assess T1 changes in
cortical bone due to heating.
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