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Abstract #0262

Imaging Temperature Changes in Cortical Bone Using Ultrashort Echo-Time MRI

Misung Han 1 , Serena J Scott 2,3 , Eugene Ozhinsky 1 , Vasant Salgaonkar 2 , Peder EZ Larson 1 , Chris J Diederich 2 , Viola Rieke 1 , and Roland Krug 1

1 Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States, 2 Radiation Oncology, University of California, San Francisco, San Francisco, CA, United States, 3 Joint Graduate Group in Bioengineering, University of California San Francisco/Berkeley, San Francisco, CA, United States

High-intensity focused ultrasound is a new, noninvasive technique to ablate bone tumors and palliate pain. MR thermometry is frequently employed to ensure proper heat deposition to the targeted tumor and to prevent unwanted damage to healthy tissues. However, conventional MR thermometry based on the proton resonance frequency (PRF) shift of water is not suitable for monitoring temperature in cortical bone due to its short T2* relaxation time. In this work, we demonstrate the ability of 3D UTE imaging to assess T1 changes in cortical bone due to heating.

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