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Abstract #0269

MR-guided focal laser ablation for prostate cancer followed by radical prostatectomy: Validation of ablation volume

Joyce GR Bomers 1 , Erik B Cornel 2 , Christiaan O Overduin 1 , Sjoerd FM Jenniskens 1 , Christina A Hulsbergen - van de Kaa 3 , Fred Witjes 4 , and Jurgen J Ftterer 1

1 Radiology, Radboud University Medical Center, Nijmegen, Gelderland, Netherlands, 2 Urology, Ziekenhuisgroep Twente, Hengelo, Overijssel, Netherlands, 3 Pathology, Radboud University Medical Center, Nijmegen, Gelderland, Netherlands, 4 Urology, Radboud University Medical Center, Nijmegen, Gelderland, Netherlands

Three patients with local prostate cancer underwent MR-guided focal laser ablation followed after three weeks by radical prostatectomy. Laser software, MR images and histopathologic specimens were used to assess the expected and actual size of the ablated region. The damage estimation maps of the laser software evidently overestimated the final ablation zone as seen in the histopathologic prostate images. The non enhancing area on the T1-weighted MR image gave a better indication of the final ablation zone.

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