Abstract #0286
Experience with q-ball language tracking in brain tumor patients
Eduardo Caverzasi 1 , Shawn Hervey-Jumper 2 , Valentina Panara 3 , Caroline A. Racine 2 , Vanitha Sankaranarayanan 4 , Nico Papinutto 1 , Kesshi Jordan 5 , Jing Li 2 , Mitchel S. Berger 2 , and Roland G. Henry 1
1
Department of Neurology, University of
California, San Francisco, San Francisco, CA, United
States,
2
Department
of Neurological Surgery, University of California, San
Francisco, San Francisco, CA, United States,
3
ITAB
- Institute of Advanced Biomedical Technologies,
University G.D'Annunzio, Chieti, Italy, Italy,
4
Department
of Radiology and Biomedical Imaging, University of
California, San Francisco, San Francisco, CA, United
States,
5
Graduate
Program in Bioengineering, UC Berkeley/UC San Francisco,
CA, United States
We show the successful application of q-ball tracking in
pre-surgical planning for language pathways in brain
tumor patients and for post-surgery white matter
tracking in order to assess postoperative tract damages.
The rating scales developed for fiber pathways damage
were found to be highly reproducible and provided
significant correlations with language deficits. The
fiber tracking spatial inter-operator reliability was
very high considering the intrinsic variability of this
technique on a voxel-wise segmentation. Our results
confirm the importance of preservation of dorsal stream
tracts (arcuate fascicle and temporo-parietal portion of
the superior longitudinal fascicle), in order to reduce
language morbidity of brain tumor patients.
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