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Abstract #0332

Fast 3D Free-breathing Abdominal Dynamic Contrast Enhanced MRI with High Spatiotemporal Resolution

Tao Zhang 1 , Joseph Cheng 1,2 , Marcus Alley 2 , Martin Uecker 3 , Michael Lustig 3 , John Pauly 1 , and Shreyas Vasanawala 2

1 Electrical Engineering, Stanford University, Stanford, California, United States, 2 Radiology, Stanford University, Stanford, California, United States, 3 Electrical Engineering and Computer Sciences, UC Berkeley, Berkeley, California, United States

Dynamic Contrast Enhanced (DCE) MRI is commonly used to detect and characterize lesions. A free-breathing DCE acquisition has high scan efficiency, but image quality can be compromised by respiratory motion. In this work, a soft-gated locally low rank parallel imaging reconstruction method is proposed for highly accelerated 3D free-breathing DCE MRI. The proposed method can significantly reduce motion artifacts, and provide high spatiotemporal resolution (approximately 1 mm 3 spatial resolution and 4 s frame rate). The proposed method has been validated on in vivo datasets.

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