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Abstract #0342

Robust adiabatic T2 preparation for fast whole brain spiral myelin water imaging at 3 Tesla

Thanh D. Nguyen 1 , Kofi Deh 1 , Ashish Raj 1 , Martin Prince 1 , Yi Wang 1 , and Susan A. Gauthier 2

1 Radiology, Weill Cornell Medical College, New York, NY, United States, 2 Neurology and Neuroscience, Weill Cornell Medical College, New York, NY, United States

An adiabatic T2prep design based on the modified BIR-4 pulse is proposed for multicomponent T2 relaxometry of the brain at 3T. When compared to the conventional composite refocusing T2prep, our results show that the proposed BIR-4 design provides more accurate T2 weighting against increased field inhomogeneities at 3T, enabling fast and reliable whole brain myelin water mapping in 10 minutes.

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