Abstract #0375
Assessment of the pancreatic shear stiffness in healthy volunteers with MR Elastography
Yu Shi 1,2 , Kevin J. Glaser 1 , Jun Chen 1 , and Richard L. Ehman 1
1
Mayo Clinic, Rochester, MN, United States,
2
Department
of radiology, Shengjing hospital, Shenyang, Liaoning,
China
This study showed that pancreatic MRE using 3D-EPI MRE
is feasible in healthy volunteers at low frequencies
(40Hz and 60Hz). The shear stiffness for each individual
subject and each pancreatic part was consistent among
the subjects (approximately 1.0-1.5 kPa at 40 Hz and
1.5-2.5 kPa at 60 Hz). Using 40-Hz vibrations might be
more suitable for pancreatic MRE than 60-Hz motion based
on the lower CV and higher ICC for inter-rater
agreements. For obese subjects, the waves are less
likely to penetrate at 60 Hz, causing noise biases and
false stiffness estimates.
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