A Wirelessly Programmable Implant Coil for Increased NMR Signal Sensitivity at Multiple Frequencies
Walker J. Turner 1 , Garrett W. Astary 2 , Barbara L. Beck 3 , Thomas H. Mareci 2 , and Rizwan Bashirullah 1
Electrical and Computer Engineering,
University of Florida, Gainesville, FL, United States,
and Molecular Biology, University of Florida,
Gainesville, FL, United States,
Magnetic Resonance Imaging and Spectroscopy Facility,
McKnight Brain Institute, University of Florida,
Gainesville, FL, United States
We propose an implantable device capable of increasing
the signal sensitivity of nuclear magnetic resonance (NMR)
measurements at multiple frequencies and field strengths
for use in monitoring bio-artificial organs
post-implantation. The device enables complete wireless
control of the resonance of a single-turn detection
coil, coupled to the already existing NMR
excitation/acquisition coil, across a wide range of
frequencies associated with important metabolic nuclei
in both 4.7Tesla and 11.1Tesla magnetic field strengths.
Device functionality was validated through NMR
experiments on tissue equivalent gel phantoms resulting
in ~2x increase in NMR signal sensitivity.
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