Model-Free Spectral Fat Analysis Based on Ultra-Dense Echo Sampling Using a Singular Value Decomposition Matrix Pencil Method

Assessing tissue fat fraction and composition is of increased clinical interest as a biomarker for various muscle and liver diseases. Here, we propose a new method to achieve an ultra-dense echo sampling in the tens of microseconds regime within clinically feasible scan times. This allows a model-free signal time course analysis based on a singular value decomposition matrix pencil method to resolve the spectral components of fat. The effect of the echo spacing and the pre-set of signal spectral components is analyzed. Four fat peaks are being resolved and the results are in agreement with literature. Reducing the preset signal components results in an underestimation of the fat percentage.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.