Abstract #0426
Bolus-tracking ASL using 3D center-out EPI trajectories in steady-state
Manoj Shrestha 1 , Toralf Mildner 1 , Torsten Schlumm 1 , Kathrin Lorenz 1 , Scott Haile Robertson 2 , and Harald E. Mller 1
1
Max Planck Institute for Human Cognitive and
Brain Sciences, Leipzig, Germany,
2
Center
for In Vivo Microscopy, Duke University Medical Center,
Durham, NC, United States
Trajectories of cylindrically-encoded 3D center-out EPI
readout were used to track an ASL bolus of well-defined
length. This was achieved by time-resolved acquisition
of single segments of k-space for a period of about 3 s
after bolus termination. The steady state created in the
imaging volume by the repeated slab selective excitation
was maintained also during the ASL bolus. All segments
of k-space belonging to the same time after ASL bolus
termination were combined and reconstructed. The
time-resolved difference images between the labeling and
control conditions clearly show the passage of the ASL
bolus inside the large brain-feeding arteries.
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