Abstract #0443
Dynamic changes of Resting State Networks depict short-term plasticity of the brain
Gloria Castellazzi 1,2 , Fulvia Palesi 2,3 , Stefania Bruno 4 , Ahmed T. Toosy 5 , Egidio D'Angelo 2,6 , and Claudia A.M. Wheeler-Kingshott 7
1
Department of Industrial and Information
Engineering, University of Pavia, Pavia, PV, Italy,
2
Brain
Connectivity Center, National Neurological Institute
C.Mondino, Pavia, PV, Italy,
3
Department
of Physics, University of Pavia, Pavia, PV, Italy,
4
Overdale
Hospital, Jersey, United Kingdom,
5
Department
of Brain Repair and Rehabilitation, UCL Institute of
Neurology, London, United Kingdom,
6
Department
of Public Health, Neuroscience, Experimental Medicine,
University of Pavia, Pavia, PV, Italy,
7
NMR
Research Unit, Department of Neuroinflammation, Queen
Square MS, UCL Institute of Neurology, London, Italy
During the execution of complex continuous cognitive
tasks, the brain elaborates information over multiple
domains and time scales, integrating it across space and
over time. In literature, only few rs-fMRI works report
how resting state networks (RSNs) change over space and
time when stimulated by external inputs. We investigated
the dynamic changes in brain activity occurring in
subjects listening to a narrated story. Results show
that RSNs respond to the stimulus with specific dynamics
of alteration and suggest the existence of a
spatiotemporal hierarchy of changes, the levels of which
depend on the specific activity each network is involved
in.
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