Abstract #0459
Shorter term aerobic exercise improves brain perfusion, cognition, and cardiovascular fitness in aging
Sina Aslan 1,2 , Sandra Chapman 2 , Jeffrey Spence 2 , Laura DeFina 3 , Nyaz Didehbani 2 , and Hanzhang Lu 4
1
Advance MRI, LLC, Frisco, Texas, United
States,
2
Center
for BrainHealth, University of Texas at Dallas, Dallas,
Texas, United States,
3
The
Cooper Institute, Dallas, Texas, United States,
4
Advanced
Imaging Research Center, University of Texas
Southwestern Medical Center, Dallas, Texas, United
States
This study adds new insights into the mounting evidence
of benefits from aerobic training revealing benefits
across cardiovascular fitness, cognition, and regional
CBF in adults. Most studies show the gains were achieved
after six months of physical training. However, the
present study shows gains across three domains earlier
than previously documented in sedentary middle-aged to
old adults. Using pCASL MRI, we measured significant CBF
gains in the anterior cingulate region which has been
linked to superior cognitive-agers in late life. The
findings suggest that healthy life style changes in
exercise habits can help to mitigate unnecessary losses.
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