Generating Quantitative Susceptibility Maps from 3D Interleaved Phase Sensitive Inversion Recovery Data.

Recent studies have shown that high quality phase sensitive inversion recovery (PSIR) data can be efficiently acquired at high magnetic field strengths using a 3D interleaved sequence in which two separate Turbo Field Echo (TFE) readouts are applied after each inversion pulse. We propose that the phase data associated with the second TFE readout of the PSIR sequence can be used to form 3D maps of magnetic susceptibility via the recently developed quantitative susceptibility mapping (QSM) technique. The results presented in this article demonstrate that T1-weighted anatomical images and iron-sensitive QSM data can be acquired simultaneously from a single scan.

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