3D Modeling of Spatial Resolution Limitations in Contrast-Enhanced MRA Related to the Contrast Bolus Profile using an Analysis of the Modulation Transfer Function

Image quality and resolution in CE-MRA depend in part on the rate, quantity and type of Gd contrast agent administered. To evaluate different injection strategies, a physiologic model of bolus delivery from the antecubital vein to the artery of interest was used to predict contrast agent concentration vs. time. Contrast agent relaxivities (T1 and T2*) in oxygenated whole blood were then used to predict signal intensity modulation during the CE-MRA acquisition, which ultimately leads to blurring in CE-MRA. Blurring was evaluated in image space for varying injections using modulation transfer function analysis.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.