Abstract #0662
In-vivo diffusion q-space trajectory imaging
Carl-Fredrik Westin 1,2 , Markus Nilsson 3 , Filip Szczepankiewicz 4 , Ofer Pasternak 1 , Evren Ozarslan 1 , Daniel Topgaard 5 , and Hans Knutsson 2
1
Radiology, Brigham and Women's, Harvard
Medical School, Boston, MA, United States,
2
Department
of Biomedical Engineering, Linkoping University,
Linkoping, Sweden,
3
Lund
University Bioimaging Center, Lund University, Lund,
Sweden,
4
Department
of Medical Radiation Physics, Lund University, Lund,
Sweden,
5
Center
for Chemistry and Chemical Engineering, Lund University,
Lund, Sweden
Here we study how the choice of diffusion MRI gradient
modulation schemes define the geometry and
dimensionality of the diffusion encoding. By defining a
diffusion encoding tensor, or diffusion measurement
tensor, we will in the Gaussian approximation regime
bring concepts as single, double, and triple-PFG into a
common framework. Careful design of the speed and shape
of the q-space trajectory can produce a planar diffusion
encoding that is isotropic in the selected plane. The
presented work shows that it is possible to perform in
vivo circular diffusion encoding imaging of the human
brain with a good SNR.
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