Increase in SNR of 370 % for 31P MR spectroscopy by adiabatic multi-echo polarization transfer and adiabatic multi-echo direct detection in one repetition time

The SNR per time unit of the signals of heteronuclear J-coupled 31P metabolites can be increased by using an adiabatic multi-echo polarization transfer technique with an even number of 180 refocusing pulses on the 31P channel combined with an adiabatic multi-echo direct detection sequence in one TR, without adversely affecting the polarization transfer or the direct detection signal. The in vivo increase in SNR for phosphomonoesters as compared to low flip Ernst angle excitation pulse acquire can be up to 370%.

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