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Abstract #0822

Improving the spatial resolution of whole-head magnetic resonance inverse imaging using partition-encoding gradient blips

Wei-Tang Chang 1 , kawin Setsompop 1 , Jyrki Ahveninen 1 , John Belliveau 1 , Thomas Witzel 1 , and Fa-Hsuan Lin 2

1 Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 2 Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan, Taiwan

Using simultaneous acquisition from multiple channels of a radio-frequency (RF) coil array, magnetic resonance inverse imaging (InI) achieves functional MRI acquisitions at a rate of 100 ms per whole-brain volume. InI accelerates the scan by leaving out partition encoding steps and reconstructs images by solving under-determined inverse problems using RF coil sensitivity information. Hence, the correlated spatial information available in the coil array causes spatial blurring in the InI reconstruction. Here, we propose a method that employs gradient blips in the partition encoding direction during the acquisition to provide extra spatial encoding in order to better differentiate signals from different partitions.

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