Meeting Banner
Abstract #0852

Preoperative imaging in patients undergoing trachelectomy for cervical cancer: validation of endovaginal T2- with diffusion-weighted MRI at 3.0T

Katherine Downey 1 , John H Shepherd 2 , Ayoma D Attygalle 3 , Steve Hazell 3 , Veronica A Morgan 4 , Sharon L Giles 4 , Thomas J Ind 2 , and Nandita M DeSouza 1

1 Clinical Magnetic Resonance Unit, Institute of Cancer Research, Sutton, Surrey, United Kingdom, 2 Department of Gynecology, Royal Marsden Hospital, Sutton, Surrey, United Kingdom, 3 Department of Histopathology, Royal Marsden Hospital, Sutton, Surrey, United Kingdom, 4 Clinical Magnetic Resonance Unit, Royal Marsden Hospital, Sutton, Surrey, United Kingdom

Combined T2-W and ZOOM-DW endovaginal MRI in women with cervical cancer treated with fertility-sparing surgery shows good correlation between MRI and histological estimates of tumor size (0.8 and 0.86 Observers 1&2, p<0.0001) and volume (0.79 and 0.52 Observers 1&2, p<0.01). Sensitivity and specificity for detecting tumors (median volume 0.31cm3) was 86.7% and 80.0% respectively. The ratio between MRI and histology measurements for length of uninvolved endocervical canal above tumor was 1.7 + 1.1 (Observer 1) 1.7 + 1.3 (Observer 2); MRI underestimated the available length of normal endocervical canal in 5% (1/19) cases.

This abstract and the presentation materials are available to members only; a login is required.

Join Here