Abstract #0855
The prognostic value of pre-treatment diffusion-weighted MRI in endometrial cancer
Kun Cao 1 , Ying-shi Sun 1 , Xiao-ting Li 1 , and Xiao-peng Zhang 1
1
Radiology department, Peking University
Cancer Hospital, Beijing, Beijing, China
It has been proved by many studies that
diffusion-weighted imaging(DWI) can provide information
about tumor biological behavior. But average ADC value
does not always work well. Quartile ADC(ADCq), derived
from statistical concepts, was created to reflect
intra-tumor heterogeneity of water movement. We had
proved that higher ADCq correlated with more aggressive
endometrial cancer. In this study, its ability in
predicting five-year-survival was tested in a cohort of
87 endometrial cancer patients. The results showed that
poorer survival were seen in tumors with high higher
ADCq, high pathological grades and deep myometrial
infiltration, but not mean ADC.
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