Parallel-transmission-enabled 3D T 2 -weighted imaging of the human brain at 7 Tesla

We use the gradient ascent pulse engineering algorithm combined with the kT-point method to design all the non-selective refocusing pulses of a SPACE sequence that mitigate severe B1+ and ΔB0 inhomogeneities. The novelty of the method lays in the optimization of the rotation matrices themselves rather than magnetization states. Three healthy subjects were scanned with a 7 Tesla scanner equipped with an 8-channel transceiver array. Exploiting the full potential of parallel transmission with the proposed methodology produced high quality whole brain T2-weighted images with uniform signal and contrast, requiring only 10 minutes of subject-specific data acquisition and pulse design.

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