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Abstract #0969

Transrectal ultrasound guided biopsy: effect on natural history of multi-parametric MRI signal and derived quantitative parameters

Arash Latifoltojar 1 , Nikos Dikaios 2 , Ashley Ridout 3 , Caroline Moore 4 , Rowland Illing 5 , Alex Kirkham 6 , Clare Allen 5 , Stuart Taylor 2 , Steve Halligan 2 , David Atkinson 2 , Mark Emberton 3 , and Shonit Punwani 2

1 Centre for Medical Imaging, University College London, London, London, United Kingdom, 2 Centre for Medical Imaging, University College London, London, United Kingdom, 3 Urology, University College London Hospital, London, United Kingdom, 4 Urology, University College London, London, United Kingdom, 5 Radiology, University College London Hospital, London, United Kingdom, 6 Radiology, university College London Hospital, London, United Kingdom

Patients with raised PSA traditionally have transrectal ultrasound guided biopsy (TRUS) performed prior to a pelvic MRI for the assessment of confirmed prostate cancer. However this approach may complicate the interpretation of MRI and cause unnecessary delay in patient management. In this work, the temporal changes in MRI quantitative derived parameters following biopsy is assessed.

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