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Abstract #0994

Diffusion sensitized ophthalmic MRI free of distortion using multi-shot RARE at 3 T and 7 T

Katharina Fuchs 1 , Jan Rieger 1,2 , Andreas Graessl 1 , and Thoralf Niendorf 1,3

1 Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrueck Center for Molecular Medicine, Berlin, Germany, 2 MRI.TOOLS GmbH, Berlin, Germany, 3 Experimental and Clinical Research Center (ECRC), a joint cooperation between the Charit Medical Faculty and the Max-Delbrueck Center, Berlin, Germany

Diffusion-weighted imaging (DWI) of the orbit is an emerging MRI application to provide guidance during diagnostic assessment and treatment of ophthalmological diseases. The standard approach for DWI is EPI. EPI is prone to severe geometric distortions, especially at high and ultrahigh magnetic fields. Realizing these constraints and the potential of ocular DWI, this work uses diffusion sensitized multi-shot RARE for ophthalmic MRI. This technique affords distortion free diffusion weighted images of the orbit, which is demonstrated in in-vivo images in healthy volunteers.

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