Abstract #0996

Ultra-High Field Optimization of the Double Inversion Recovery (DIR) sequence: Gray Matter Imaging at 7T

Eberhard Daniel Pracht ¹ , Daniel Brenner ¹ , Alard Roebroeck ² , and Tony Stcker ¹

¹ German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany, ² Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Netherlands

Gray matter imaging is an important technique for cortical lesion detection in neurological disorders, such as epilepsy and Alzheimer's. It is increasingly performed utilizing the DIR sequence. The aim of this project was to optimize the DIR Turbo-Spin-Echo (TSE) sequence for ultra-high field application to benefit from the overall SNR gain at high field. Therefore typical high field issues such as B0 /B1 inhomogeneities and SAR limitations had to be addressed. Furthermore an efficient fat suppression technique had to be implemented to enhance image quality significantly.

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