Abstract #1000
High resolution whole brain diffusion imagining at 7T for the Human Connectome Project
An T. Vu 1 , Edward Auerbach 1 , Christophe Lenglet 1 , Steen Moeller 1 , Julien Sein 1 , Pierre-Francois Van de Moortele 1 , Kamil Ugurbil 1 , and Essa Yacoub 1
1
University of Minnesota, CMRR, Minneapolis,
MN, United States
Mapping the structural connectivity in healthy adults
for the Human Connectome Project requires high quality,
high resolution, multiband (MB)-accelerated whole brain
diffusion MRI (dMRI). Higher fields provide higher SNR
and the opportunity to acquire at higher resolution, but
at the cost of increased B1+ inhomogeneity (resulting in
signal loss in regions such as the cerebellum and
temporal lobe) and SAR (limiting our ability reduce TR
or accelerate). This abstract describes the steps we
have taken to facilitate high resolution, whole brain
dMRI at 7T, enabling cortical layer specific anisotropy
and FA previously only seen in ex-vivo human studies.
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