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Abstract #1044

Impact of positional difference on the measurement of breast density in MRI

Jeon-Hor Chen 1,2 , Siwa Chan 3 , Yi-Ting Tang 4 , Angela T. Cheriyan 1 , Nikita Rakesh Shah 1 , and Min-Ying Su 1

1 Center for Functional Onco-Imaging, University of California, Irvine, California, United States, 2 Department of Radiology, Eda Hospital and I-Shou University, Kaohsiung, Taiwan, 3 Department of Radiology, Taichung Veterans General Hospital, Taichung, Taiwan, 4 Department of Medical Imaging, China Medical University, Taichung, Taiwan

We conducted a study to investigate the consistency of percent breast density measured in MRI in four different positions and imaging resolution. The breast and fibroglandular tissue segmentation was based on an established novel method. Results of FV and PD measurement show small variations, with an averaged CV of <9%, among the four MR studies. Remarkable measurement variation did occur in some subjects in hands-down position, compared to hands-up position. The results from our MR consistency study indicate that MR imaging data from multi-centers, regardless of patients positions (hand-up or hands-down), can be combined for analysis.

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