Abstract #1048
A Simulation Study of the Flexible TWIST View Sharing Impact on the Breast DCE MRI
Yuan Le 1 , Marcel Dominik Nickel 2 , Randall Kroeker 2 , Christian Geppert 2 , Brian Dale 2 , Hal D. Kipfer 3 , and Chen Lin 1
1
Radiology and Imaging Science, Indiana
University School of Medicine, Indianapolis, Indiana,
United States,
2
Siemens
Healthcare, North Carolina, United States,
3
Radiology
and Imaging Science, Indiana University School of
Medicine, Indiana, Indiana, United States
The acquisition of breast DCE-MRI using a flexible TWIST
view sharing technique was simulated. A digital
phantom was generated with three 5mm uniform spherical
lesions of persistent, plateau and wash-out type
of contrast uptake, and one 10 mm complex tumor with a
mixture of all three types of enhancements. Our results
show that with the typical spatial resolution in
clinical breast DCE-MRI, TWIST view sharing parameters
of pA=20% and pB=20% provides the lowest overall RMS
error for all time points, while pA=50% and pB=50%
produces image with minimum error at the peak contrast
uptake.
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