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Abstract #1062

Quantitative evaluation of diffusion weighted imaging techniques for radiotherapy of prostate cancer

Gary Liney 1,2 , Thahabah Mohammed Al Harthi 3 , Ewa Juresic 4 , Lynette Cassapi 4 , Lois Holloway 4 , Mark Sidhom 4 , David Manton 5 , and Peter Gibbs 6

1 Medical Physics, Ingham Institute for Applied Medical Research, Sydney, NSW, Australia, 2 Physics, University of Wollongong, Sydney, NSW, Australia, 3 Physics, University of Sydney, NSW, Australia, 4 Cancer Therapy Centre, Liverpool Hospital, NSW, Australia, 5 Radiation Physics, East Riding, United Kingdom, 6 University of Hull, East Riding, United Kingdom

The measurement of apparent diffusion coefficient (ADC) from diffusion weighted imaging (DWI) has been linked to tumour response following radiotherapy in prostate cancer. For it to be used to monitor and adapt plans during a course of treatment DWI needs to be produce reliable measurements and distortion free images. This work compares three DWI techniques in phantoms and prostate volunteers in order to assess their suitability for use as a robust clinical tool.

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