MR imaging of water and fat in cortical bone: comparison between the SWIFT and FSE sequences

Bone diseases have influenced millions of peoples lives, and MR imaging of bone is thus important and has attracted attentions of researchers and clinicians for a long time. However, bone imaging still remains a challenge for MRI, as bone, especially cortical bone, has a relatively short T2 and T2* values, which results in a fast signal decay. In this work, we aim to conduct a preliminary study to image free water stored in a sample of a swine humerus bone by using the fast spin echo (FSE) sequence and the sweep imaging using Fourier transformation (SWIFT) sequence. To get a qualitative mapping of free water distribution in the bone, MR scans were performed before and after dehydration of the sample, with fat and water saturation applied. The results demonstrate that the SWIFT sequence has an advantage on visualizing cortical bone compared with the FSE sequence, especially on visualizing bound water component in cortical bone.

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