Abstract #1188
Sodium, CEST and T2* of Human Achilles tendon in Subjects after Ciprofloxacin Treatment
Vladimir Juras 1,2 , Pavol Szomolanyi 1,2 , Benedikt Hager 1 , Marek Chmelik 1 , Stefan Zbyn 1 , Jan Vosshenrich 1 , and Siegfried Trattnig 1
1
High Field MR Centre, Department of
Biomedical Imaging and Image-Guided Therapy, Medical
University of Vienna, Vienna, Austria,
2
Department
of Measurement Science, Slovak Academy of Sciences,
Bratislava, Slovakia
This study showed that sodium MRI is sensitive enough to
visualize macromolecular alterations which are present
after ciprofloxacin treatment. Interestingly, gagCEST
does not demonstrate this ability, although the p-value
for BULK was only slightly above 0.05. T2* reflects
mostly the water and collagen interplay, therefore, no
change was observed. In conclusion, sodium MRI was
proven to be a potential marker for Achilles
tendinopathy after ciprofloxacin treatment.
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