Abstract #1237
Quantitative skeletal muscle NMR imaging of juvenile dermatomyositis patients
Pierre G Carlier 1 , Noura Azzabou 1 , Paulo Loureiro de Sousa 1 , Benot Florkin 2 , Emmanuel Deprez 3 , Norma B Romero 4 , Sverine Denis 5 , Valrie Decostre 6 , and Laurent Servais 7
1
AIM-CEA Institut de Myologie, Laboratoire
RMN, Paris, France,
2
CHR
La Citadelle, Service de Pdiatrie, Lige, Belgium,
3
CHU
de Lige, Service anatomie et cytologie pathologiques,
Lige, Belgium,
4
AIM,
Institut de Myologie, Laboratoire d'histopathologie,
Paris, France,
5
Centre
de rfrence des maladies neuromusculaires, CHR La
Citadelle, Lige, Belgium,
6
AIM,
Institut de Myologie, Laboratoire de physiologie et
d'valuation neuromusculaire, Paris, France,
7
AIM,
Service Essais Cliniques et Bases de Donnes, Paris,
France
The existence of oedematous/inflammatory/necrotic
lesions is subjectively appreciated on T2-weighted
images. Because it relies on identification of
hyperintensities between and within muscles, the
interpretation risk with T2-weighted images is to miss
global, homogenous increases in T2. We demonstrate here
this concern to be more than theoretical. Three patients
aged 6, 7 and 12 were referred for suspicion of
dermatomyositis. Standard T2w imaging was normal or
subnormal. Quantitative T2 maps showed that muscle water
T2s were abnormally elevated in the limb girdles and
lower limbs. Quantitative T2 mapping can be required to
detect unambiguously muscle lesions as here in juvenile
dermatomyositis.
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