Abstract #1252
            MRI signal texture parameters within human intervertebral discs as biomarkers of spine pathologies and severities
                      Delphine Perie                     1,2                    , Clemence Balosetti                     1,2                    , 						Sofiane Achiche                     1                    , and Hubert Labelle                     2          
            
            1
           
           Mechanical Engineering, Ecole Polytechnique 
						de Montral, Montreal, QC, Canada,
           
            2
           
           Research 
						Center, CHU Sainte Justine, Montreal, QC, Canada
          
            
          In both scoliosis and spondylolisthesis, the progression 
						of the spine deformation leads to the degeneration of 
						intervertebral discs characterized by a change in its 
						structure and biochemical composition. The MRI images of 
						79 patients (32 with scoliosis, 32 with 
						spondylolisthesis and 15 with herniated discs) were 
						analysed using texture parameters extracted from the 
						intensity histograms of the grey level, contrast, 
						correlation, energy and homogeneity images. The results 
						validated our hypothesis: the calculated tissue-specific 
						texture features can effectively discriminate the 
						pathologies and some of their severities. This method 
						has the advantage of supporting the interesting 
						possibility of developing robust non-invasive predictive 
						methods for the diagnosis of the severities of spine 
						pathologies.
         
 
            
				
					How to access this content:
					For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
					After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
					After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
					Click here for more information on becoming a member.