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Abstract #1300

MR-compatible normobaric gas mixer for hypercapnic vasoreactivity studies on humans

L. Lamalle 1,2 , J.-B. Menut 3 , S. Vergs 4 , J. M. Warnking 5,6 , and A. Krainik 7,8

1 Inserm US 17, Grenoble, France, 2 Universit Grenoble Alpes UMS IRMaGe, Grenoble, France, 3 SMTEC, Sport & Medical Technologies S.A., Nyon, Switzerland, 4 Universit Grenoble Alpes Laboratoire HP2, Grenoble, France, 5 Inserm U836 (quipe 5), Grenoble, France, 6 Universit Grenoble Alpes Grenoble Institut des Neurosciences, Grenoble, France, 7 Universit Grenoble Alpes Facult de Mdecine, Grenoble, France, 8 CHU de Grenoble Unit IRM, Grenoble, France

A normobaric gas mixer was developed to allow MR-based hypercapnic vasoreactivity studies on humans. It operates safely close to the magnet and can be remotely computer controlled. Hypercapnic episodes with FiCO 2 less than 10 % can be programmed to chain in succession for prescribed numbers of MR scanner trigger events. Device performance is demonstrated in a cerebral BOLD block-designed fMRI experiment.

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