Abstract #1396
Validation of a PET-derived Respiratory Signal by Comparison with an MRI Pencil-Beam Navigator Signal in Simultaneous PET/MR
Richard Manber 1 , David Atkinson 1 , Anna Barnes 2 , Brian Hutton 1 , Celia O'Meara 2 , Sebastien Ourselin 1 , Simon Arridge 1 , and Kris Thielemans 1
1
University College London, London, United
Kingdom,
2
University
College London Hospital, London, United Kingdom
Respiratory gating in PET imaging is common practice to
correct for motion. It has previously been shown that a
respiratory signal can be extracted from PET list-mode
data using Principal Component Analysis (PCA). We
demonstrate the validity of this signal by showing a
strong correlation with the gold-standard MRI
navigator signal, simultaneously acquired on 9 patients
with a range of PET tracers, and by showing comparable
PET gating results based on the PET and MRI derived
respiratory signals respectively. Finally we show
improvements in image sharpness of motion corrected
images, formed by warping and combining gates.
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