Abstract #1405
Wireless MR active marker based PET motion correction in simultaneous brain MR-PET
Chuan Huang 1 , Jerome L Ackerman 2 , Yoann Petibon 1 , Marc D Normandin 1 , Georges El Fakhri 1 , and Jinsong Ouyang 1
1
Center for Advanced Medical Imaging
Sciences, Massachusetts General Hospital, Harvard
Medical School, Boston, MA, United States,
2
Athinoula
A. Martinos Center for Biomedical Imaging, Massachusetts
General Hospital, Harvard Medical School, Boston, MA,
United States
Recently, wireless active markers have been used in head
motion tracking/correction in brain MRI due to its
improved patient safety, ease-of-use and simpler
manufacturing. Head motion is even more a problem in
brain PET since dynamic brain PET can last more than an
hour. Furthermore, anesthesia is often used to keep
animals still during brain PET acquisitions, but many
studies showed that anesthesia can also perturb the
neurological process under study. Simultaneous MR-PET is
a novel hybrid modality generated substantial interest
in recent years. Complementary information of the brain
from PET and MR can be simultaneously obtained. This new
modality also opens the possibility to use MR active
marker derived motion information for PET motion
correction. In this work, we demonstrate in phantom and
non-human primate studies the use of wireless active
markers to track head motion and incorporating the
measure motion information in the list-mode PET
reconstruction to obtain PET images without motion
artifacts in simultaneous MR-PET.
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