Meeting Banner
Abstract #1408

Direct evaluation of MR-derived attenuation correction maps for PET/MR of the mouse myocardium

Eleanor Evans 1 , Guido Buonincontri 1 , Rob C Hawkes 1 , Richard E Ansorge 2 , T. Adrian Carpenter 1 , and Stephen J Sawiak 1,3

1 Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, United Kingdom, 2 Department of Physics, University of Cambridge, Cambridge, United Kingdom, 3 Behavioural and Clinical Neurosciences Institute, University of Cambridge, Cambridge, United Kingdom

Attenuation correction (AC) must be applied to provide quantitative measurements of Positron Emission Tomography (PET) tracer activity concentrations. The gold standard AC method involves passing a transmission source around the subject and surrounding scanner equipment. Due to the limited space in PET/MR scanners, MR-derived AC (MRAC) must be used instead. This is problematic as MR signals are not directly related to the amount of gamma radiation absorbed. By comparing to gold standard transmission scans, we found a single tissue region MRAC segmentation approach, derived from whole body MRI, provided accurate myocardial SUV values in mice.

This abstract and the presentation materials are available to members only; a login is required.

Join Here