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Abstract #1428

QUANTITATIVE ANALYSIS OF LATERAL GENICULATE NUCLEUS (LGN) IN GLAUCOMA USING 7.0T MRI

Hye-Jin Jeong 1 , Jong-Yeon Lee 2 , Jong-Hwan Lee 2 , Sang-Han Choi 1 , Young-BO Kim 1 , and Zang-Hee Cho 1

1 Neuroscience Research Institute, Gachon University, Incheon, Korea, 2 Department of Ophthalmology, Gachon University Gil Hospital, Incheon, Korea

Glaucoma is characterized by progressive degeneration of retinal ganglion cells (RGC) and their axons. Recent neuroimaging studies in human glaucoma have demonstrated degenerative changes in the visual pathway of brain including lateral geniculate nucleus (LGN). However, a precise assessment of the LGN is still a technical challenge due to anatomic characteristics. Therefore, our aim was to investigate the LGN atrophy in patients with open-angle glaucoma using high-resolution 7.0 Tesla MR imaging and correlation with retinal nerve fiber layer (RNFL) thickness

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