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Abstract #1436

En Route to Probing Human Myocardial Microstructure in vivo Using Susceptibility Based MRI at 7.0 T

Till Huelnhagen 1 , Fabian Hezel 1 , and Thoralf Niendorf 1,2

1 Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrueck Center for Molecular Medicine, Berlin, Germany, 2 Experimental and Clinical Research Center, a joint cooperation between the Charite Medical Faculty and the Max Delbrueck Center, Berlin, Germany

The complex microstructure of the myocardium is pivotal for cardiac function and can provide important information about the underlying (bio)physical principles and (patho)physiological mechanisms. Probing human myocardial fiber structure in vivo has been described, but remains challenging due to cardiac and respiratory motion. Susceptibility based MRI provides excellent contrast which can be used to investigate tissue microstructure and track fibers in the brain. Recognizing this opportunity the work explores the applicability of susceptibility weighted MRI for probing human myocardial microstructure in vivo at 7.0 T.

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