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Abstract #1443

Multi-dimensional Susceptibility Conditioned RF Pulse (SCOPE) Design: A Spokes Approach

Wei Feng 1 , Yang Xuan 2 , and E Mark Haacke 3

1 Radiology, Wayne State University, Detroit, Michigan, United States, 2 Radiology, Wayne State University, MI, United States, 3 Wayne State University, MI, United States

A novel multi-dimensional spokes RF pulse design method is proposed to compensate for bulk susceptibility-induced phase variations. Under the small flip angle regime, there is a Fourier relationship between the excitation pattern and the RF and gradient waveforms, which traverses the excitation k-space. The conventional spokes pulse design approach is modified such that the cost function incorporates both magnitude and phase constraints inside the desired region of interest (ROI) based on susceptibility field map, while the phase is allowed to vary arbitrarily outside the ROI. Numerical Bloch simulations and imaging experiments were performed for 1D, 2D and 3D pulse design applications. It is shown that the proposed method is viable and could have significant potential in susceptibility-related imaging applications.

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