Abstract #1443
            Multi-dimensional Susceptibility Conditioned RF Pulse (SCOPE) Design: A Spokes Approach
                      Wei Feng                     1                    , Yang Xuan                     2                    , and E Mark 						Haacke                     3          
            
            1
           
           Radiology, Wayne State University, Detroit, 
						Michigan, United States,
           
            2
           
           Radiology, 
						Wayne State University, MI, United States,
           
            3
           
           Wayne 
						State University, MI, United States
          
            
          A novel multi-dimensional spokes RF pulse design method 
						is proposed to compensate for bulk 
						susceptibility-induced phase variations. Under the small 
						flip angle regime, there is a Fourier relationship 
						between the excitation pattern and the RF and gradient 
						waveforms, which traverses the excitation k-space. The 
						conventional spokes pulse design approach is modified 
						such that the cost function incorporates both magnitude 
						and phase constraints inside the desired region of 
						interest (ROI) based on susceptibility field map, while 
						the phase is allowed to vary arbitrarily outside the 
						ROI. Numerical Bloch simulations and imaging experiments 
						were performed for 1D, 2D and 3D pulse design 
						applications. It is shown that the proposed method is 
						viable and could have significant potential in 
						susceptibility-related imaging applications.
         
 
            
				
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