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Abstract #1454

Local and global SAR constrained large tip angle 3D kt points parallel transmit pulse design at 7 T

Filiz Yetisir 1 , Bastien Guerin 2 , Lawrence L. Wald 2,3 , and Elfar Adalsteinsson 1,3

1 Dept. of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States, 2 Martinos Center for Biomedical Imaging, Dept. of Radiology, Massachusetts General Hospital, Charlestown, MA, United States, 3 Harvard-MIT Division of Health Sciences Technology, Cambridge, MA, United States

Explicit SAR constraints have been proven useful for slice selective small tip angle pulse design. We propose a nonselective pulse design method that explicitly constrains local SAR and RF peak amplitude at large tip angle and demonstrate that when local SAR is controlled directly rather than via control of peak RF voltage, safer pulses with better excitation profiles are obtained. Our method is more practical than Tikhonov regularized strategies since it only requires one run to ensure that all the limits (SAR and RF) are satisfied.

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