Abstract #1465
Fat-suppressed Alternating-SSFP for Whole-Brain fMRI Using a Short Spatial-Spectral Pulse
Tiffany Jou 1 , Steve Patterson 2 , John M. Pauly 1 , and Chris Bowen 2
1
Electrical Engineering, Stanford University,
Stanford, CA, United States,
2
Physics
and Atmospheric Science, Dalhousie University, Halifax,
NS, Canada
Alternating-SSFP (alt-SSFP) suppresses banding artifacts
and allows for whole-brain fMRI in a single run by using
RF catalyzation to alternate between RF phase-cycling
steady states. However, bright fat signal remains a
problem because of the short TR used. Without an
effective fat suppression technique, artifacts like fat
chemical shift and off-resonance signal instability
result. Our goal was to design a spectral-spatial (SPSP)
pulse short enough to be used for alt-SSFP fMRI, with
reduced fat chemical shift artifacts and improved
temporal SNR (tSNR) time-courses. In this study, we
propose our SPSP fat-suppression method as the first
practical implementation of alt-SSFP and demonstrate
good BOLD sensitivity in both breath-hold and visual
paradigms.
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