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Abstract #1469

Optimization of Flip angle and TR schedules for MR Fingerprinting

Maxwell L Wong 1 , Eric Z.C. Wu 2 , and Eric C Wong 3

1 UC San Diego, La Jolla, California, United States, 2 University of Southern California, California, United States, 3 Department of Radiology and Psychiatry, UCSD, La Jolla, California, United States

In this study, we simulate and attempt to optimize parameters for MR Fingerprinting. We looked for ways to characterize flip angle and TR schedules that produce the best estimated T1, T2 and frequency maps. This was done using frequency filters applied to random schedules, and comparison to DESPOT1 and DESPOT2 to assess the effectiveness of MRF. We confirmed higher sensitivity of MRF compared to DESPOT, and identified frequency characteristics in the flip angle schedules that were beneficial.

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