Volume-Selective Thin Slice Thickness EPI for Whole Brain fMRI: Comparison with Z-Shimming EPI

The slice thickness of slices in a small region of the human brain, where large MRI signal loss was experienced due to susceptibility difference at the air-tissue interfaces, was set to half the thickness of slices located at other regions where the static magnetic field was homogeneous. The MRI signal loss was dramatically recovered. Compared with z-shimming technique, images acquired by this volume-selective thin slice thickness technique have lesser temporal signal to noise ratio. However, thin slice thickness technique worked better for slices close to brain stem which cover amygdala and hippocampus areas.

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