An interleaved multi-shot scheme involving self-refocused single-scan SPEN that is immune to in-plane movement and phase shifts

Recent studies have shown the benefits of a single-shot spatiotemporal encoding (SPEN): reducing magnetic field inhomogeneity distortions and delivering chemical shift information. The present work demonstrates that SPEN can also exhibit substantial motion immunity, even when executed in interleaved multi-shot schemes. Shots of SPEN data can be co-processed to generate full FOV images without requiring extra reference scans. Since no aliasing is involved, a phase correction from SPEN shots can be estimated, resolving ghost-free SPEN images, and eliminating transient phase shifts or in-plane movement between shots. Preliminary tests confirm the advantages on phantom and human scans, including functional MRI experiments.

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