Estimation of the arterial input function using accelerated dual-contrast EPIK: a multi-modality MR-PET study
Liliana Caldeira 1 , Seong Dae Yun 1 , Nuno A da Silva 1 , Christian Filss 1 , and N Jon Shah 1,2
Institute of Neuroscience and Medicine - 4,
Research Centre Jlich GmbH, Jlich, Germany,
of Neurology, RWTH Aachen University, Aachen, Germany
The arterial input function (AIF) is essential for
quantification in MRI and PET imaging. The ground truth
for AIF estimation is arterial cannulation.
Alternatively, the AIF can be estimated using MRI and/or
PET images, but a reasonable temporal resolution of
dynamic image series is necessary (<2s). In PET imaging,
high temporal resolution is limited (>5s). Here, we
propose a method to acquire data for the AIF based on an
EPI with keyhole (EPIK) sequence. The EPIK sequence
combines both high temporal resolution and high spatial
resolution. Furthermore, dual-contrast EPIK (DC-EPIK)
can also be acquired to provide additional information.
This abstract and the presentation materials are available to members only;
a login is required.