Constrained Source Space Imaging: Rapid Point Measurement of fMRI Paramaters

A novel technique to rapidly measure fMRI parameters has been improved upon. Our technique uses a modified PRESS sequence to excite three arbitrarily positioned voxels. SENSE is then used to reconstruct each of the four voxels time-dependent signal. A minimum TR of 73 ms was achieved, and showed to provide good agreeance between a single voxel measurement. This technique provides access to T2, T2* and centre frequency, all which can be used to monitor functional activity through the BOLD response. This technique will be used to measure very fast brain activity for mental chronometry in the future.

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