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Abstract #1685

Simultaneous Acquisition of the 3D Displacement Vector in Magnetic Resonance Elastography of the In Vivo Human Brain

Dieter Klatt 1 , Curtis L. Johnson 2 , Temel K. Yasar 3 , Joseph L. Holtrop 2,4 , Bradley P. Sutton 2,4 , Thomas J. Royston 1 , and Richard L. Magin 1

1 The Richard and Loan Hill Department of Bioengineering, The University of Illinois at Chicago, Chicago, Illinois, United States, 2 Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States, 3 Mechanical and Industrial Engineering, The University of Illinois at Chicago, Chicago, Illinois, United States, 4 Bioengineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States

SampLe Interval Modulation Magnetic Resonance Elastography (SLIM-MRE) enables the simultaneous acquisition of the 3D displacement vector through direction-dependent shifting of motion encoding gradients relative to the applied vibration. In this study, we have embedded a SLIM-MRE acquisition scheme into a multishot, variable-density spiral imaging sequence and have determined the cerebral mechanical properties of three volunteers. Our findings suggest that SLIM reduces MRE scan time and allows immediate co-registration of the three displacement components without compromising inversion results.

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